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Pathology and in vivo imaging studies have identified superficial plaque erosion as a frequent and important mechanism underlying acute coronary syndromes (ACS). In contrast with plaque rupture, the pathophysiological mechanisms leading to plaque erosion remain poorly understood. The advent of intravascular imaging techniques, particularly optical coherence tomography, has aided understanding

This changes the behaviour of endothelial cells and primes the Nrf2 system, which under normal situations helps protect the endothelium. Smoking is a known risk factor for plaque erosion. 2020-10-01 2021-02-01 56.3% plaque erosion in STEMI patients presented with noncritical stenosis, having distinct morphological features from erosion with critical stenosis. Fibrous plaque and nearby bifurcation were independently associated with the presence of noncritically stenotic plaque erosion, remaining a desire to tailor treatment therapy to individual patients. 2016-02-26 2019-12-30 2018-03-13 Request PDF | Plaque Erosion | Plaque rupture and erosion are the two most common causes of acute coronary syndromes (ACS). Although plaque rupture has been well-characterized | Find, read and Fig. 8.1 Angioscopic finding of plaque erosion and rupture. (a) Plaque erosion, only reddening with no evidence of trans-cap ruptures, (b) plaque rupture, perforation of a fibrous cap overlying lipid core Fig. 8.2 Coronary angiography and intravascular imaging in patient with ST-segment elevation myocardial infarction not related to plaque rupture.

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Mar 31, 2021 Endothelial erosion of atherosclerotic plaques is the underlying cause of approximately 30% of acute coronary syndromes (ACS). As the

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Disclosures. Research Grants/Support. Haemonetics. Idorsia. Feb 1, 2019 Yet plaque rupture and erosion occur on atherosclerotic plaques with markedly different histological features, suggesting substantial differences Aug 27, 2020 Plaque erosion is caused by endothelial damage or denudation and overlying thrombosis in the absence of frank cap rupture.
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Compared to plaque erosion, plaque rupture more often showed positive remodeling (p=0.003) with a larger necrotic core area examined by virtual histology (VH)-IVUS, while negative remodeling was prominent in plaque erosion.

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Unstable plaques are vulnerable to spontaneous erosion, fissure, or rupture, causing acute thrombosis, occlusion, and infarction long before they cause stenosis

Current smoking was the predominant coronary risk factor of plaque erosion rather than dyslipidemia, hypertension, chronic kidney disease, or diabetes mellitus, and plaque erosion was most frequently located in the LAD with a limited focal Pathology and in vivo imaging studies have identified superficial plaque erosion as a frequent and important mechanism underlying acute coronary syndromes (ACS). In contrast with plaque rupture, the pathophysiological mechanisms leading to plaque erosion remain poorly understood. The advent of intravascular imaging techniques, particularly optical coherence tomography, has aided understanding • Plaque erosion was the underlying pathology in ¼ of patients with ACS. • Anti-thrombotic therapy without stent implantation effectively reduced thrombus volume and increased flow area without recurrent ischemic events at 1 month. 10 • Randomized trials will be needed to reproduce this pilot data Plaque Erosion as a Mechanism of Acute Coronary Syndromes (ACS) JN Learning™ is the home for CME and MOC from the JAMA Network.

processes in both clinical settings - plaque rupture (RFC) and plaque-erosion plaques types and (c) to test its prognostic implications in patients after ACS.

Shopping. Tap to unmute. If playback doesn't begin shortly, try restarting your device. Request PDF | Plaque Erosion | Plaque rupture and erosion are the two most common causes of acute coronary syndromes (ACS).

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