2 Apr 2016 The dGEMRIC index (mean ± sd) at four times (min ± sd) after intravenous injection of double dose Magnevist. The dGEMRIC index was 20–30

The dGEMRIC index is highly correlated to mechanical stiffness. A generalized relationship was found to provide good correspondence across sources and regions. Use of the dGEMRIC index as a predictive measure of stiffness is possible, depending on the application's acceptable error. Copyright (c) 2007 Orthopaedic Research Society. PMID: 17427215

An intraobserver analysis for T1 analysis was made in 10 randomly selected SCFE hips. The alpha angle was measured in T1 parasagittal images as defined by Nötzli 24 . For example, adherence to an exercise regimen was shown to increase the dGEMRIC Index [48, 59, 60]. Similarly, in obese subjects, quadriceps strength was shown to correlate positively with dGEMRIC , as did weight loss . In the knees with radiographic OA, the dGEMRIC index at baseline was lower than that in the knees without radiographic OA (P = 0.03). CONCLUSION: The results of the present study support the dGEMRIC index as a clinically relevant measure of cartilage integrity and suggest that a low index may be predictive of the development of knee OA. using T1(Gd) as the dGEMRIC Index as a measure of Gd-DTPA2-distribution may be less suitable at 3T than 1.5T. However, T1(Gd) as an index may prove to be clinically useful.

PMID: 17427215 2006-11-01 · The mean T1 (Gd) within a clinically relevant region of articular cartilage is usually referred to as the dGEMRIC Index 6. In the current dGEMRIC protocol, Gd-DTPA 2− is administered per kilogram body weight with the assumption that the distribution volume of the contrast agent is proportional to body weight. We found that the dGEMRIC index decreased to a substantially higher degree in operatively treated patients with FAI compared with nonoperative management at 1-year followup. The baseline dGEMRIC index correlated with the improvement in the WOMAC score 1 year postoperatively.

Average T1 for Four Slices Patient T1 (ms) Control T1 (ms) No. Sex/Age Anterior Posterior Sex/Age Anterior Posterior 1 F-19 630 569 F In a previous dGEMRIC study using bulk (full-thickness) index values, we found higher dGEMRIC index interpreted as better cartilage quality in exercising compared to sedentary healthy volunteers .

Table 10 Operative group was divided according to combined baseline acetabular and femoral dGEMRIC cutoff of 332 ms (combined acetabular and femoral dGEMRIC index-1 SD) Full size table In the posterosuperior quadrant, the dGEMRIC index was higher (592 ± 203 ms versus 444 ± 205 ms; p < 0.001) for patients with intact cartilage compared with

Methods One hundred and forty-eight women (one knee for each subject) aged ≥40 years were included 10 List of Papers I Tiderius C J, Tjörnstrand J, Akeson P, Sodersten K, Dahlberg L, Leander P. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC): intra- and interobserver va The dGEMRIC index has been shown to be affected by factors, such as exercise , body mass index , and early-stage OA . This imaging method has been validated in clinical studies comparing histological and biochemical measurements of GAG content ( Figure 9 ) [ 104 ].

Delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC) is based on the theory that Gd‐DTPA2− will distribute in inverse relation to cartilage glycosaminoglycan (GAG). T1Gd (T1 after penetration of a

average dgeMriC indices (in Milliseconds) for the 12 regions of interest, the Medial and lateral Compartments at Baseline and after Follow-up. - "Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy" The dGEMRIC index was calculated as the average of the T1 values for the acetabular and femoral head cartilages. Results: The dGEMRIC index correlated with both pain (rs = -0.50, p < 0.0001) and the lateral center-edge angle (rs = 0.52, p < 0.0001), whereas the joint space width did not correlate with either, with the numbers available.

Voxel-wise fitting of the dGEMRIC signal using the Levenberg-Marquardt nonlinear least-squares method with in-house developed software (R2015a, The MathWorks, Natick, MA, USA) produced a reconstructed T1 map.
Mosfet module wiring

dGEMRIC index was lower compared to non-injured controls. 2007-04-12 Delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC) is a technique to evaluate cartilage quality by estimation of glycosaminoglycan (GAG) content, a low dGEMRIC index indicates low cartilage quality. The characteristic resistance to compressive forces of healthy cartilage relies on high GAG content. dGEMRIC INDEX In the medial compartment, the mean dGEMRIC Index was 14.4% lower (374 61 ms, mean SD) than in the lat-eral reference compartment (437 59 ms, mean SD), consistent with a lower GAG content medially (P<0.001). There was no difference in the dGEMRIC Index between men and women (P¼0.46 medial, P¼0.85 lateral).

However, T1(Gd) as an index may prove to be clinically useful. Alternatively, further dGEMRIC studies could be performed at 1.5T, or at 3T with higher doses of Gd-DTPA2-and/or concurrent measurement of T1o. T1o T1(Gd) T1, ms 300 500 700 900 1100 1300 Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) reflects cartilage glycosaminoglycan (GAG) distribution. The technique assumes that the plasma levels of the contrast agent Gd-DTPA2− are the same across individuals after intravenous (IV) injection, when dosing by weight.
Köpmannagården karlshamn facebook

evolution gaming omsättning
princip redovisning ab brantingsgatan stockholm
buy safe
odd molly t-shirt
spädbarn sätter i halsen amning
julian

3 Mar 2017 (MR) imaging of cartilage (dGEMRIC) indexes ac- quired with different gadolinium-based contrast agents (GB-. CAs), with emphasis on the

unpublished. Cartilage metabolic MR- and synovial fluid studies indicate that ACL To compare the delayed gadolinium-enhanced magnetic resonance (MR) imaging of cartilage (dGEMRIC) indexes acquired with different gadolinium-based contrast agents (GBCAs), with emphasis on the difference in electrical charge, and to evaluate the feasibility of the use of GBCAs other than gadopentetate dimeglumine with a double negative charge (Gd-DTPA 2−) as alternatives at dGEMRIC. The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage [1,2,3,4,5,6].Most studies have analysed bulk values, i.e. a mean post-contrast T1 value in full-thickness cartilage regions of interest (ROI), also referred to as the “dGEMRIC index” []. dGEMRIC index of MCP joints with initially severe synovitis and less severe synovitis in an intra-individual assessment. This underlines the importance of an early treatment in eRA to reduce further cartilage damage of the inflamed joints.

Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) reflects cartilage glycosaminoglycan (GAG) distribution. The technique assumes that the plasma levels of the contrast agent Gd-DTPA2− are the same across individuals after intravenous (IV) injection, when dosing by weight. However, adipose tissue has lower extracellular water (ECW) than lean tissue. The aims of this study were to measure

The anterior center-edge angle, the joint space width, and the presence of a labral tear were all found to be associated with osteoarthritis in the univariate analysis.

Change dGEMRIC index (ms)-200-100 0 100 200 300 p=0.016 MR1 MR2 dGEMRIC index (ms) 240 280 320 360 400 p=0.20 p=0.002 p=0.23 p=0.092 BMI and meniscectomy Meniscectomy Neuman et … dGEMRIC index in the medial weight-bearing cartilage.